Preheat oven to 350°F. Lightly grease a 9x13-inch baking dish.
In a large mixing bowl, stir together cream of chicken soup, chicken broth, sour cream, 4 tablespoons melted butter, onion powder, garlic powder, poultry seasoning, pepper, and salt.
Add cooked chicken and uncooked rice. Stir until evenly combined.
Spread mixture into the prepared baking dish. Cover tightly with foil.
Bake for 45 minutes.
Remove foil and gently stir the casserole.
Sprinkle cheddar cheese over the top.
In a small bowl, mix crushed crackers with 2 tablespoons melted butter. Sprinkle over the cheese.
Bake uncovered for 15 to 20 minutes, or until the rice is tender and the casserole is hot and bubbly.
Let rest for 10 minutes before serving.