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Melt-In-Your-Mouth Chicken Breast (Easy Family Favorite)

Tender, juicy chicken breasts coated in a creamy Parmesan mixture and baked until golden and delicious. This easy family favorite is perfect for busy weeknights and special enough for Sunday dinner.
Prep Time 10 minutes
Cook Time 45 minutes
Total Time 55 minutes
Servings 6

Ingredients

  • 6 boneless, skinless chicken breasts
  • 1 cup mayonnaise
  • 1/2 cup grated Parmesan cheese
  • 1 tsp garlic powder
  • 1 tsp onion powder
  • 1/2 tsp seasoned salt
  • 1/2 tsp black pepper
  • 1/2 tsp paprika

Instructions

  • Preheat oven to 375°F.
  • Lightly grease a 9×13-inch baking dish with nonstick cooking spray.
  • Pat chicken breasts dry with paper towels and arrange them in a single layer in the prepared baking dish.
  • In a medium bowl, combine:
    Mix until smooth mayonnaise, Parmesan cheese, garlic powder, onion powder, seasoned salt, black pepper, and paprika.
  • Spread the Parmesan mixture evenly over the tops of the chicken breasts.
  • Bake uncovered for 40–45 minutes, or until the chicken reaches an internal temperature of 165°F and the topping is lightly golden.
  • Allow the chicken to rest for 5 minutes before serving.

Notes

  • Chicken breasts that are especially thick may benefit from being pounded to an even thickness before baking.
  • Greek yogurt can be substituted for mayonnaise if desired.
  • Freshly grated Parmesan provides the best flavor.
  • Leftovers store well in the refrigerator for up to 3 days.